- Raman Microscopes
- Transmission Raman
- Modular and Fiber Coupled Raman
- Triple Raman Spectrometers
- OEM Miniature Raman
Raman Microscopes
HORIBA Scientific’s fully automated Raman microscopes allow fast non-destructive chemical micro-analysis and automated high definition Raman chemical imaging.
A Raman microscope is used in many varied applications, including characterization of graphene/CNT materials, pharmaceutics, forensics, geology, materials and life science – full details can be found in the applications section of this site.
Transmission Raman
The Transmission Raman accessory is available for most of the HORIBA range of Raman microscope systems. It enables Transmission Raman spectroscopy to be undertaken in a simple and efficient format - all upon the standard Raman microscope. It provides a cost effective access to a technique ideally suited to bulk chemical analysis of opaque samples, including powders and tablets.
True bulk analysis via transmission Raman
Transmission Raman is based on the collection of Raman light propagating through the sample in the direction of the excitation laser – in essence, the sample is illuminated with the excitation laser from one side, and the Raman signal is collected from the other. Unlike its more traditional back-scattering counterpart which is vastly predominant in most dispersive Raman systems, the transmission configuration allows analysis of the full volume through which the light travels, even for opaque samples.
The Transmission Raman Accessory provides fast, reliable information about:
- API concentration
- Polymorphs analysis
- Crystallinity
- Powder composition and purity
- Content uniformity
- Solid form
Easy measurements with no sample preparation
As in classical Raman spectroscopy, transmission Raman is non-contact, non-invasive and non-destructive. It requires no sample preparation. Importantly, the measurement is insensitive to particle-size effects, sample homogeneity and orientation.
Top: Transmission Raman spectra from four tablets with varying API dosage (where percentages indicate variation relative to the standard production dosage). Bottom: plot of API peak intensity versus concentration, showing excellent linearity.
Modular and Fiber Coupled Raman
The range of modular Raman spectrometers from HORIBA Scientific allows the user to build a Raman experiment from the ground up and to undertake high performance Raman spectroscopy at a price to fit most budgets.
The rugged fiber coupled HE spectrometer is fully optimized for high throughput QC and process Raman analysis.
Customized solutions are also possible, including adaptation for specific processes such as fthe Eluxyl simulated countercurrent adsorption process for para-Xylene production.
Triple Raman Spectrometers
Overview
In recent years there has been a sharp increase in the number and form of analyses to which Raman spectroscopy has been applied. The introduction of small bench-top spectrometer systems has certainly opened up the fields of study. However, on the back of the renewed interest in the Raman technique, ever more demanding applications have arisen.
For this reason the next generation of Research grade instruments incorporate much of the cutting edge technology found in the bench-top systems, but also provide the higher performance required for samples which prove difficult or impossible to analyze with more routine instrumentation.
The T64000 system is designed to provide a versatile platform for Raman analysis. It has an integrated triple spectrometer design for unprecedented optical stability. The instrument incorporates the proven technology of the confocal LabRAM Raman microprobe. The mechanical coupling is rigid and stable. The optical coupling is efficient and throughput is limited only by theoretical considerations.
Features
- Double Subtractive Stage
- Triple additive
- Direct Single Spectrometer
High stray light rejection Holographic notch filter technology provides a very good solution to laser rejection for visible wavelengths in many applications.However, there are acknowledged limitations to the use of these filters for work close in to the laser line. Even with specially developed low frequency accessories(4) with many difficult samples it is still often impossible to obtain reliable data at 10 , 20 or 30 cm-1.In using the double subtractive configuration of the T64000, it is possible to obtain spectral information very close in to the laser line. The subtractive mode is ideal for studying such detail as LA modes in polymer systems and crystal lattice modes.
Spectrum of a proprietary SiGe material in which it is possible to observe spectral bands down as low as 4 cm-1.Ultra high resolutionWith the use of the ultra-high resolution triple additive configuration of the T64000 triple system, it is possible to very accurately study the position of Raman bands.This is of particular importance for the measurements of stress in semiconductor materials such as GaN, SiC and diamond where stress induced shifts in the order of 0.1 cm-1 are often studied. The high resolution also offers the level of accuracy required for the authentication and certification of materials for Raman standards.Single spectrometer technologyWith the final mode of operation, the direct spectrograph entrance, the system can be used with holographic notch filter technology and as a more conventional single spectrometer based system. The high throughput of the large optical components means that it is then ideal for Raman mapping and even remote probe forms of analysis.
Raman Mapped image of Stressed Silicon interface using Single direct path operation.UV Raman SpectroscopyThe T64000 has many benefits for deep UV Raman measurements.
- The high stray light rejection enables lower frequency Raman bands below 100cm-1 to be observed even in the deep UV (244nm). It can provide a complete spectral analysis not limited in its scope or range.
- The tune-ability of the double filter stage enables all the various deep UV frequencies to be accessed easily, (eg. 227-290nm). Hence, optimizing resonance enhancement for particular species of components (eg. proteins from DNA).
- The specialized UV-VIS microscope option is adapted to working over a broad spectral range, without the need of optics to be removed or replaced. It preserves the high spatial discrimination across the wavelengths. It also offers specialized UV enhanced image viewing of the sample, and all of the standard Raman mapping facilities.
- The spectral resolution of the 640mm focal length, as with the LabRAM HR system enables Raman analysis to be maintained at a standard to high spectral resolution. The resolution of ~1.4 cm-1/pixel far improves upon the ~4 cm-1/pixel resolution of the small bench-top instrument found in the UV.
Summary
The list of applications to which the T64000 can be applied is impressive including, thin films, solid state devices, biological chemistry and techniques such as UV, resonance Raman, PL and laser fluorescence.In Summary, for demanding applications and work which requires high laser rejection, high spectral resolution and the obvious advantages of a continuously variable laser filter, the triple spectrometer system is an invaluable tool. With the introduction of the latest technology from the smaller bench-top systems it can also be applied to more general routine analysis. The T64000 heralds a new era for new and more versatile high grade research Raman instrumentation.
Specifications
|
Focal length |
640mm, all stages |
|
Aperture** |
f/7.5 |
|
Dispersion** Additive triple |
0.23 nm/mm |
|
Dispersion** Single (direct or subtractive double) |
0.7 nm/mm |
|
Gratings |
76 x 76 mm2; selection from over 50 gratings including the patented PAC gratings |
|
Drive mechanism |
Sine bar |
|
Step Size* |
0.00066 nm |
|
Mechanical range* |
0 to 1000 nm (and above) |
|
Slits |
0 to 2 mm wide; 0.5,1.,2.5,5,15 mm high |
|
(subtractive intermediate) |
0 to 50 mm wide; 0 to 15 mm high |
|
(spectrograph entrance) |
0 to 25 mm wide, 0 to 15 mm high |
|
Spectrograph port |
25 - 30 mm clear aperture |
|
*Based on 1800 gr.mm gratings, **dependant upon wavelength |
Spectral Resolution and Coverage
|
Configuration |
Single (direct or double filter stage) |
Additive Triple |
|
|
Grating (gr/mm) |
Mechanical Range |
CCD Coverage (1")** |
CCD Coverage (1")** |
|
300 |
0-6000 nm |
133 nm |
38.0 nm |
|
600 |
0-3000 nm |
62 nm |
21.0 nm |
|
1200 |
0-1500 nm |
30 nm |
9.1 nm |
|
1800 |
0-1000 nm |
17 nm |
5.7 nm |
|
2400 |
0-750 nm |
11 nm |
4.1 nm |
|
3600 |
0-500 nm |
6 nm |
2.0 nm |
** 1 nm corresponds to ca.
100 cm-1 at 320 nm
40 cm-1 at500 nm
15 cm-1 at 750 nm
OEM Miniature Raman
HORIBA Scientific supplies a complete range of miniature Raman systems and components for OEM industrial applications ranging from pharmaceutical and medical ones to forensic and security, semiconductor and other high volume industries.
Mini spectrometer + 785nm laser + probe
All fiber optic coupled
High volumes of miniaturized Raman spectrometers can be manufactured with great affordability.
We only quote for OEM volumes starting around 50-100/year, and do not design and prototype miniaturized and customized Raman spectrometers, probes and lasers for one off production and single users.
Miniature Raman spectrometers are available with uncooled CCDs (Sony ILX-511B, S9840, S11071 and S10420) and TE cooled low cost CCDs (E2V CCD-30, S7031) and more high end E2V CCDs.
The range covered by our mini spectrometers and compact Raman probes cover 200-400cm-1 up to 1800-3500 cm-1. Our OEM engineering is focused on providing customized systems.
Our OEM laser solutions come with TE cooling and built-in wavelength stabilization, at 532, 660 and 785nm (more on request) and range in power from 50mW to 350mW (or more for challenging detection limits).
For one-off system purchases, please consider our standard Raman systems or customisable modular Raman systems.
For further information and quotation on prototypes and volume please visit our OEM Miniature Raman webpages.
Amazing size for Miniature Raman spectrometer : about 64 x 89 x 32mm
