XploRA ONE™ - Simply better Raman

 

Overview

The XploRA ONE™ is the highly versatile, yet easy to use, Raman microscope targeted at the industrial and routine analytical sector.  It combines optical microscopy, with sensitive Raman analysis in a “ONE shot “ analysis concept.  Raman has never been so easy and yet so powerful in the Analytical Lab.

The XploRA ONE™ offers simplicity in design and operation so that the analyst can focus on the sample measurements and routine analysis that is important, obtaining results not just spectra.

It provides class leading sensitivity and confocal detail, full optical microscopy and even has options for HORIBA’s innovative SWIFT™ Raman chemical imaging, yet requires minimal operator training and maintenance. The XploRA ONE™ philosophy ensures that Raman has become an even more accessible analytical technique.

Ideal for applications driven measurements:

  • QA/QC analysis

  • Raw material validation

  • Forensic routine analysis

  • Pharmaceutical testing

  • Routine inspection

Features

The XploRA ONE™ is the highly versatile Raman microscope that combines ease of use with functionality and performance for the analytical lab:

  • Non-destructive testing and analysis
  • No sample preparation
  • Ideal for chemical analysis and identification
  • Spectral databases – for simple interpretation of results
  • Automate your Raman analysis– with user defined measurement methods
  • Auto-calibration software– ensures your data is always accurate
  • Affordable entry into full confocal performance– up to 1µm XY resolution
  • Upgradeable to SWIFT fast confocal Raman imaging
  • 532nm or 785nm high brightness CLS lasers for optimal results
  • Higher sensitivity for speed and improved limits of detection
  • Single “one-shot” data acquisition for the full Raman range
  • Automated particle location and chemical ID with ParticleFinder
  • Suitable for high throughput screening measurements with MultiWellmodule.

Specifications

Laser options:

Integrated internally - 532nm or 785nm CLS high brightness lasers optimised for micron resolved measurements

Spectral range:

100cm-1 to 3500cm-1 minimum rnage in  ONE-shot  operation  (depending upon laser)

Spectrograph:

Imaging flat field spectrometer for use with large area CCD detector
High throughput/sensitivity

Laser power control:

6 position ND filter module - PC controlled

Detector:

1024x256 TE air-cooled scientific CCD, USB control, no maintenance vacuum, 16 bit and up to 1.48 MHz readout speed.  Offering improved sensitivity and fast Raman acquisition.

Microscope:

Materials/clinical light microscope. Optimised for stability with high quality optics and ergonomic design. Includes Kohler illumination for transmission and reflection illumination, abbe condenser, 10x and 50x objectives (100x objective optional)

Confocal sampling:

Rugged confocal spatial filtering, offering maximum 1µm x1µm lateral resolution for micron scale Raman analysis and imaging (where 100x objective used).

Computer:

Desktop PC with monitor, keyboard and mouse, pre-loaded with Windows 7TM 32-bit and LabSpec 6 spectral software suite

Environment / Dimensions

Weight:

35Kg (77lbs)

Size (WxHxD):

449mm x 626mm x 352mm

Operating temperature:

15oC -28oC optimal environmental temperature range

Voltage:

110/240 VAC  standard mains supply

Other:

#no water cooling or LN2 supply required

Raman Links:

Accessories

 

A range of accessories and options are available for the XploRA ONE Raman microscope, including XY mapping stage, SWIFT fast Raman imaging, heating/cooling stage, macro cuvette sampler, microscope objectives,  CDRH class (1) enclosure and various software modules.

Download Datasheet 

XploRA™PLUS

 

Overview

Raman imaging has never been so fast!

Incorporating unique and powerful functions in a reliable, high performance system, ideally suited to the research and analytical lab, the XploRA PLUS is our best multi-sample, multi-user Raman microscope ever.

It is fully confocal, not compromising image quality, spatial or depth resolution. The SWIFT Fast Raman images are the fastest fully confocal Raman images available, typically 10x faster than conventional Raman imaging.

The simplicity and power of the XploRA PLUS is unmatched with an enhanced range of options such as multiple laser wavelengths, EMCCD detection, Raman polarisation and even Raman-AFM combination.

Features

  • SWIFTTM 10x faster Raman imaging
  • Improved detection and sensitivity
  • Full Confocality  for complete image detail
  • Full optical microscope so you can see your samples
  • Maximum detail, resolution and range for enhanced spectroscopy
  • HORIBA’s OneClick easy Raman analysis
  • NIST traceable and patented Autocalibration options for validated results
  • Ultimate optical stability- robust, reliable, long term operation
  • Automated operation offering simple, powerful reliability
  • 2 year base unit warranty as standard

Future-proof Expansion

  • Compatible with atomic force microscopes for combined Raman-AFM and TERS (Tip Enhanced Raman Spectroscopy)
  • Multiple laser wavelengths – ensures optimal results and minimised fluorescence interference from the widest range of sample types
  • Full system automation with software control and intuitive operation – non-expert operators can get results fast
  • Comprehensive Raman spectral libraries for fast Raman chemical identification
  • Automated particle location and chemical ID with ParticleFinder
  • Suitable for high throughput screening measurements with MultiWellmodule.

Download Datasheet

XP Examina

 

Overview

The XploRA Examina™ is the highly versatile, yet easy to use Raman microscope targeted at the Forensic analytical sector.  It combines optical microscopy, with sensitive Raman analysis in a “ONE shot “analysis concept.  Raman has never been so easy and yet so powerful in the Forensic Lab.

The XploRA Examina™ offers simplicity in design and operation so that the Forensic analyst can focus on the sample measurements and routine analysis that is important, obtaining results not just spectra.

It provides class leading sensitivity and confocal detail, full optical microscopy yet requires only minimal operator training and maintenance. With HORIBA’s innovative SWIFT™ Raman chemical imaging system and KIA database as standard the Examina™ is ideally matched to the needs of the busy Forensic Laboratory. The XploRA Examina™ philosophy ensures that Raman has become an even more accessible analytical technique for the Forensic analyst.

Features

The XploRA Examina™ is available in 2 options; the XploRA Examina One™and the XploRA Examina Plus™, these systems are based on the renown and extremely well tested XploRA ONE and XploRA Plus™ Raman Microscope systems but they have been configured to perfectly match the requirements of Forensic examinations. The XploRA Raman Microscopes have an excellent reputation as highly versatile Raman microscope that combine ease of use with functionality and performance for the analytical lab.

The main features of the two systems are:

  • XploRA Examina One™

  • XploRA Examina Plus™

Raman in Forensics

Raman is an ideal technique for Forensic science offering high quality data, reliability and significant speed advantages over other analytical techniques. Benefits for the analysis of trace samples not only include the range of samples that can be analysed but also in the non-destructive nature of the analysis. Raman microscopy enables easier comparative analysis, unknown chemical identification and improved value for money.

Microsope Image of 3 white fibres

Raman spectroscopic analysis gives chemical "fingerprint" identification of fibres, paint chips, explosives, GSR, Inks and narcotics/controlled drugs - virtually all types of trace analysis. Whereas Raman chemical imaging gives the ability to chemically image a sample to see layers, optical section samples, and to see sample homogeneity or contaminants.

Colour coded Raman image of a tablet

Colour coded Raman image of a tablet highlighting the spatial distribution of the various chemical components

 

The full confocal sensitivity of the  XploRA Examina™ enables sub-micron scale particles to be isolated from the background and analysed, whilst HORIBA's unique SWIFT Fast Raman imaging enables sample regions of interest to be spectroscopically located and analysed. Minimal sample preparation and ease of in-situ analysis is ideal for the measurement of unknown and potentially hazardous samples

With more than 5000 samples in the optional spectral databases and additional commercial databases available, Raman identification becomes easy and reliable. An advanced Mixture analysis module can cope with complex mixture of powders and liquid samples, whilst functional group analysis can help identify important “chemical markers”.

Benefits of Raman XploRA Examina™

Validation

  • NIST traceable calibration standards and Standard “SOP”’s
  • Patented autocalibration (focus free, ASTM, NIST traceable) ensures data is always correctly validated and its precision assured
  • CFR 21 electronic records optional module provides data logging and authenticity

Specification

XploRA Examina One™ - package Ref. XP ONE-XPEF-1
Research grade microscope, 10x, 50x objectives, macrosampler, 3MP top camera, reflected and transmitted light illumination, polarised light, motorised XY and Z motor, class (I) safety, computer with pre-installed LS6.3 software, spectral database, 785 nm 100 mW CLDS laser

XploRA Examina Plus™ - package Ref. XP PLUS-XPEF-3
Research grade microscope, 10x, 50x LWD,100x objectives, macrosampler, 3MP top camera, trinoc with eyepieces reflected and transmitted light illumination polarised light, motorised XY and Z motor, class (I) safety, Computer with pre-installed LS6.3 software., spectral database, 532 nm, 638 nm,785 nm CLDS lasers

Download Datasheet

LabRAM HR Evolution

 

Overview

The LabRAM HR Evolution Raman microscopes are ideally suited for both micro and macro measurements, and offer advanced confocal imaging capabilities in 2D and 3D. The true confocal Raman microscope enables the most detailed images and analyses to be obtained with speed and confidence. With guaranteed high performance and intuitive simplicity, the LabRAM HR Evolution is the ultimate instrument for Raman spectroscopy.  They are widely used for standard Raman analysis, photoluminescence (PL), tip enhanced Raman scattering (TERS) and other hybrid methods.

View the LabRAM HR Evolution Video

Features

High spatial and spectral resolutions
HORIBA Scientific’s optimized design results in the most sensitive instruments on the market, with high throughput diffraction limited spatial resolution. Spectrally, the high resolution spectrometer allows subtle sample information such as crystallinity, polymorphism, strain and other band analysis to be characterized with ease.

Cover your sample from UV to NIR
Compatibility with a wide range of laser wavelengths and the possibility of mounting up to three detectors enables the measurement wavelength range to be extended from 200nm to 2100nm. The optimized UV configuration offers the best solution for UV Raman analysis with wavelengths below 400nm. Such performance opens up other spectroscopic techniques such as UV Raman, resonance Raman and photoluminescence, allowing detailed sample characterization from many varied materials.

Ease of use and ergonomy
The fully automated intelligent design of the LabRAM HR Evolution ensures ultimate performance coupled with ease of use; and the LabSpec 6 softwareallows full benefit from the unrivalled performances of the LabRAM HR Evolution at the touch of a button.

Ultra-fast confocal imaging
The LabRAM HR Evolution includes the unique SWIFT™ and DuoScan™ fast Raman imaging technologies.
DuoScan™ is a confocal imaging mode, with high precision, ultra-fast rastering mirrors creating variable sized laser macro-spots, and also allowing nano-step mapping from deep UV to NIR. 
SWIFT™ offers confocal Raman mapping with CCD integration times down to 1 ms per point and below.

The unique combination of innovative optics, detectors and software combine to provide true confocal Raman imaging with an unmatched speed of data acquisition.

Raman-AFM and TERS compatible
The integral flexibility of the LabRAM HR Evolution means that it is the ideal platform for combined Raman-AFM analysis, and research to TERS (tip enhanced Raman scattering) nano-Raman

Ultra-Low Frequency Module
The LabRAM HR Evolution combines simple access to very low frequencies down to 5cm-1 with a high throughput single stage spectrometer, using the ULF Module. The new generation of notch and bandpass filters allows additional sample characterization to be made in a spectral region rarely available with other basic spectrometers.

Automated particle location and chemical ID
ParticleFinder offers a user friendly tool for automated location, characterization and Raman analysis of particles. Hundreds or thousands of particles can be quickly located and characterized using the LabRAM HR Evolution’s advanced Raman capabilities.Find the best conditions for the analysis of your sample
The sampling flexibility of the LabRAM HR Evolution ensures that your research can be fully optimized. Standardly equipped with the upright microscope, an open-space microscope can be installed giving you free space under the objective to adapt numerous accessories like large cryostats, broad travel range stages…  For life science research, the inverted microscope offers ideal sampling for cells and tissues.

CaptuR laser trapping
A unique and integrated laser trapping solution ideal for fine particle control during microscopic analysis.

Furthermore, the Transmission Raman accessory can be easily installed on the LabRAM HR Evolution for bulk analysis of opaque/turbid materials; and the SuperHead probes enable in-situ monitoring of reactions or remote analysis.

Download Datasheet

XploRA INV

 

Overview

The XploRA INV combines the exclusive automation features and small footprint of the standard XploRA™ Raman microscope with the unique sampling capabilities of an inverted microscope, especially important for demanding biological applications. These applications include:

  • cell research
  • disease detection
  • characterisation of drug-cell interactions
  • pharmaceutical verification of intercellular activities

In addition, the inverted geometry allows easy incorporation of AFM units for combined Raman-AFM and TERS (Tip Enhanced Raman Spectroscopy) for highest spatial resolution sample visualisation.

The open structure of the XploRA INV also permits the use of virtually all options and add-ons for inverted microscopes, including micro manipulators and “optical tweezers”, specific enclosures for cell applications, etc.

XploRA INV sample stage equipped with micro-injector
XploRA INV sample stage equipped with micro-injector

The XploRA INV also offers the option to integrate the unique scanning capabilities of HORIBA’s patented DuoScan for rapid spectroscopic multichannel Raman imaging, as well as the new 3D FCI (Fast Confocal Imaging) module, which allows ultra-fast fluorescence imaging for visualisation and verification.

White light imagefluorescence FCI imagehyperspectral fluorescence image

 

 

 

 

 

White light image (left), fluorescence FCI image (center) and hyperspectral fluorescence image (right) images of a bovine embryo after staining with Nile Red, acquired on the XploRA INV.  The hyperspectral image illustrates the stain in different polarity states.  Data courtesy of Prof. Igor Chourpa, Université de Tours, France.

Download Datasheet